永久性心房纤颤患者中医体质类型与血浆D-二聚体相关性研究

Study on Correlation Between Constitution Types of TCM and Plasma D-dimer in Patients with Permanent Atrial Fibrillation

目的:探讨永久性心房纤颤患者中医体质类型与血浆D-二聚体之间的相关性。方法:选取2017年1月至2018年9月广安门医院和广安门医院南区收治的永久性心房纤颤患者150例作为研究对象,进行血浆D-二聚体水平检测,填写《中医体质分类与判定表》,对数据进行统计分析。结果:永久性心房颤动患者中医体质涵盖所有9种体质类型,其所占比例及血浆D-二聚体水平(%,ng/mL)分别为气虚质(40.6%,292.48±334.58),痰湿质(18.0%,324.74±346.78),血瘀质(10.0%,643.3±1627.23),阳虚质(9.3%,396.64±404.01),阴虚质(8.6%,432.46±664.35),气郁质(6.6%,133.7±79.37),湿热质(3.3%,122.00±21.62),平和质(2.6%,252.00±263.03),特禀质(0.6%,13)。结论:永久性心房纤颤患者中气虚质及痰湿质所占比例较大,血浆D-二聚体水平血瘀质>阴虚质>阳虚质>痰湿质>气虚质>平和质>气郁质>湿热质>特禀质,男女患者血浆D-二聚体水平无明显差别,患者血浆D-二聚体水平不受年龄的影响。

Objective: To explore the correlation between constitution types of TCM and plasma D-dimer in patients with permanent atrial fibrillation. Methods: A total of 150 patients with permanent atrial fibrillation admitted in the inpatient department and the Southern Branch of Guang′anmen Hospital from January 2017 to September 2018 were selected as research objects.Their plasma D-dimer levels were detected,each Classification and judgment table of TCM Constitution Type was filled in,and the data were analyzed statistically. Results: The TCM constitutions of patients with permanent atrial fibrillation covered all 9 constitution types.Their proportions and plasma D-dimer levels(%,ng/mL)were:qi-deficiency constitution(40.6%,292.48±334.58),phlegm-dampness constitution(18.0%,324.74±346.78),blood-stasis constitution(10.0%,643.3±1627.23),yang-deficiency constitution(9.3%,396.64±404.01),yin-deficiency constitution(8.6%,432.46±664.35),qi-obstruction constitution(6.6%,133.7±79.37),dampness-heat constitution(3.3%,122.00±21.62),balanced constitution(2.6%,252.00±263.03),and allergic constitution(0.6%,13),respectively. Conclusion: The proportions of qi-deficiency constitution and phlegm-dampness constitution in patients with permanent atrial fibrillation were larger.Plasma D-dimer level:blood-stasis constitution>yin-deficiency constitution>yang-deficiency constitution>phlegm-dampness constitution>qi-deficiency constitution>balanced constitution>qi-obstruction constitution>dampness-heat constitution>allergic constitution.There was no significant difference in plasma D-dimer level between male and female patients.The plasma D-dimer level was not affected by age.