中医药治疗肝肾阴虚型帕金森病的研究进展

Research Progress of Parkinson's Disease with Liver and Kidney Yin Deficiency by Chinese Medicine

帕金森病是一种常见的老年病,其病程长且并发症多,难以根治,临床上,长期服用多巴胺等西药会出现药效减退、精神障碍及异动症等不良反应。中医辨证论治帕金森病,认为肝肾亏虚是本病的发病基础,且与风、痰、瘀相关。治疗上注重培补肝肾、平肝熄风、补肾活血等,从整体角度调节帕金森病,对帕金森病运动症状和非运动症状均有着良好的疗效且无明显不良反应。近年来,中医治疗帕金森病更加注重从辨证的角度来调节非运动症状。现将近5年中医治疗肝肾阴虚型帕金森病的临床研究进行归纳整理,综述如下。

Parkinson′s disease(PD)is a common geriatric disease. It has a long course and many complications,which is difficult to cure. Clinically,long-term use of western medicine such as dopamine may cause adverse effects,such as hypothermia,mental disorders and dyskinesia. According to the TCM syndrome differentiation,the liver and kidney deficiency is the basis of the PD,which is related to wind,phlegm,and blood stasis. The treatment of TCM focuses on nourishing liver and kidney,calming liver and eliminating wind,invigorating kidney and promoting blood circulation. Chinese medicine treatment has good curative effects on the motor symptoms and non-motor symptoms of PD without obvious side effects. In recent years,Chinese medicine treatment of Parkinson′s disease has paid more attention to regulating non-motor symptoms from a dialectical point of view. The research progress on Parkinson′s disease with liver and kidney yin deficiency by Chinese medicine in the past 5 years was summarized as follows.