二氢青蒿素的合成工艺研究

Study on Synthesis of Dihydroartemisinin

以青蒿素为原料,硼氢化钠为还原剂,经过液体形式加入,在均相体系下进行反应,避免了固液混悬反应的缺点,降低了反应安全风险。具备工业化应用价值。

Artemisinin was used as raw material,sodium borohydride was used as reducing agent,and the reaction was carried out in homogeneous system through liquid addition,which avoided the shortcomings of solid-liquid suspension reaction and reduced the reaction safety risk.It has the application value of industrialization.