烧伤创疡再生医疗技术与负压封闭引流技术序惯应用在慢性难愈合创面治疗中的效果分析

Clinical Efficacy of the Sequential Application of MEBT/MEBO and Vacuum Sealing Drainage(VSD)in the Treatment of Chronic Non-healing Wounds

目的分析探讨烧伤创疡再生医疗技术与负压封闭引流技术序惯应用在慢性难愈合创面治疗中的临床疗效。方法对2013年12月至2018年1月德阳市人民医院烧伤整形美容科收治的132例慢性难愈合创面患者序惯应用烧伤创疡再生医疗技术与负压封闭引流技术治疗,部分面积较大的创面待肉芽组织生长旺盛后予以Ⅱ期缝合、植皮或皮瓣移植等方式封闭创面,观察治疗效果。结果创面Ⅰ期愈合者97例,平均愈合时间为28 d;行Ⅱ期手术封闭创面者25例,其中植皮封闭创面者20例、皮瓣移植封闭创面者5例,且最终创面均完全愈合,平均愈合时间为42 d;因拒绝手术或有手术禁忌症未行手术封闭,且创面始终未愈者10例,平均住院时间为66 d。结论序惯应用烧伤创疡再生医疗技术与负压封闭引流技术治疗慢性难愈合创面,可有效促进肉芽组织生长,加速创面愈合,疗效显著,临床应用价值较高。

Objective To analyze and investigate the clinical efficacy of the sequential application of MEBT/MEBO and vacuum sealing drainage(VSD)in the treatment of chronic non-healing wounds.Methods 132 patients with chronic non-healing wounds admitted into the Burns and Plastic Surgery Department of Deyang People’s Hospital between December 2013 and January 2018 were treated with the sequential application of MEBT/MEBO and VSD.For some largesized wounds,secondary suture,skin grafting or skin flap transplantation were performed to close the wounds when the granulation tissues grew well.The clinical efficacy was observed.Results The wounds of 97 patients realized the primary healing,with the mean healing time being 28 d.25 patients underwent secondary surgeries to close the wounds,of which 20 patients received skin grafting and 5 patients received skin flap transplantation,and the wounds were all completely healed at the end,with the mean healing time of 42 d.The wounds of 10 patients remained non-healing because they refused to undergo surgeries or had surgical contraindications,and their mean hospitalization length was 66 d.Conclusion The sequential application of MEBT/MEBO and VSD in the treatment of chronic non-healing wounds can effectively promote the growth of granulation tissues and wound healing,presenting a much high clinical application value.