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免疫球蛋白对脓毒症患者血管内皮功能的影响 被引量:3

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摘要 目的:探究静脉注射免疫球蛋白对脓毒症患者血管内皮功能的影响。方法:遴选2016年3月-2018年3月笔者所在医院收治的80例出现血小板减少的脓毒症患者为研究对象,按照治疗意愿将其分为对照组与观察组,对照组给予常规治疗,观察组在对照组基础上增加静脉注射免疫球蛋白,观察两组患者血管内皮功能情况、血小板计数等指标。结果:两组治疗前及治疗第1天PLT比较,差异无统计学意义(P>0.05),治疗第3天以后,观察组PLT升高情况明显高于对照组,差异有统计学意义(P<0.05);两组治疗前及治疗前3 d TM、vWF、APACHEⅢ评分情况比较,差异无统计学意义(P>0.05),治疗第5天以后,观察组TM、vWF、APACHEⅢ评分情况明显低于对照组,差异有统计学意义(P<0.05)。结论:对脓毒血症患者采用静脉注射免疫球蛋白治疗能有效减少血小板减少的相关症状,能有效减轻对患者血管内皮细胞造成的损伤,改善患者的出血倾向,值得临床推荐使用。
作者 贺周香
出处 《中外医学研究》 2019年第15期52-53,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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