妊娠期肾巨大血管多发平滑肌脂肪瘤1例报告并文献复习

A Case Report and Literature Review of Giant Multiple Renal Angiomyolipoma in Pregnancy

目的:探讨妊娠期肾血管平滑肌脂肪瘤(RAML)的临床特征、诊断及治疗方法。方法:通过回顾性分析1例28岁孕8周的女性RAML患者的临床表现、诊断及治疗方法,结合相关文献复习,探讨该疾病的生物学行为、诊断及治疗方法。结果:CT检查提示肾血管平滑肌脂肪瘤,其最大层面大小约19.1 cm×13.3 cm×31.5 cm,患者在施行选择性肾动脉栓塞术的基础上进行了肿瘤剜除术,并且在术后2个月的随访中没有发现复发迹象。结论:妊娠期肾血管平滑肌脂肪瘤临床上少见,患者常把腹部的隆起误认为妊娠的正常现象而延误疾病的诊治。对于处于备孕期患有肾血管平滑肌脂肪瘤的女性,应采取积极的预防性治疗措施。

Objective:To explore the clinical characteristics and analyze the diagnosis and treatment of renal angiomyolipoma(RAML)in pregnancy.Method:We retrospectively reported a case of 28 years old woman with a giant multiple RAML at 8 weeks of pregnancy,and reviewed the relevant literatures.The biological behavior of RAML was recorded,the diagnosis and treatment of these lesions were discussed.Result:RAML was suspected by computed tomography(CT),which showed the tumor was about 19.1 cm×13.3 cm×31.5 cm,and the patient underwent enucleation of the lesion follow by selective renal arterial embolization.The patient was uneventful after the operation and remains well,with no evidence of recurrence over 2-mouth follow-up.Conclusion:The cases of RAML in pregnancy are rare,patients often consider the enlargement of abdomen is normal phenomenon of pregnancy.Therefore,diagnosis and treatment is delayed.Prophylactic treatment is necessary for women who are ready to get pregnant.