2017年度参加全国生物剂量估算能力考核结果分析

Analysis of national assessment results of biological dose estimation ability in 2017

目的通过对2017年参加全国生物剂量估算能力考核总结分析,提高该项工作的专业技术能力。方法根据《2017年度生物剂量估算能力考核方案》,进行受照后的培养、制片、分析染色体的非稳定性畸变,统计染色体非稳定性畸变数量(dic+r),应用国家标准上的曲线Y=7.3512×10^-3+3.4037×10^-2D+8.0398×10^-2D2估算剂量。结果样本05-1平均值是3.62Gy,95%的可信区间是(3.32~3.90)Gy,相对偏差为0.56%;样本05-2平均值是2.37Gy,95%的可信区间是(2.19~2.54)Gy,相对偏差为7.73%,两样品相对偏差均<20%,综合判定本实验室生物剂量能力估算结果为合格。结论本实验室能满足生物剂量工作需要,但仍然需要加强质量控制,规范操作,不断总结分析,建立本实验室生物剂量曲线,减少系统误差,使结果更加准确可靠,为核与辐射事故的临床救治及监督管理提供科学依据。

Objective Through the summary and analysis of the national assessment of biological dose estimation ability in 2017, the professional and technical ability of this work was improved.Methods According to the "Assessment Program of Biological Dose Estimation Ability in 2017", the unstable chromosome aberrations were cultured, produced and analyzed after irradiation. And the number of unstable chromosome aberrations(dic+r) was counted. The dose was estimated by using the curve Y=7.3512×10^-3+3.4037×10^-2D+8.0398×10^-2 D2 in the national standard.Results The average of sample 05~1 is 3.62 Gy, the 95% confidence interval is(3.32~3.90)Gy, and the relative deviation is 0.56%. The average of sample 05~2 is 2.37 Gy, the 95% confidence interval is(2.19~2.54)Gy, the relative deviation is 7.73%, and the relative deviation of both samples is less than 20%. It is concluded that the estimated results of biological dose ability in our laboratory are qualified.Conclusion The laboratory can meet the needs of biological dose work, but it still needs to strengthen quality control, standardize operation, constantly summarize and analyze, establish the biological dose curve of the laboratory, reduce systematic errors, make the results more accurate and reliable, and provide scientific basis for clinical treatment and supervision and management of nuclear and radiation accidents.