影响桂北地区隐性梅毒患者生活质量的多因素分析

Multi-factor Analysis of Quality of Life Affecting Patients with Recessive Syphilis in Northern Guangxi

目的探讨桂北地区梅毒患者生活质量的影响因素。方法对2015年1月-2018年1月本院门诊诊治的370例梅毒患者进行分析,分析患者临床资料、SF-36量表及SDS量表评分结果;并行多元逐步线性回归分析SF-36影响因素。结果梅毒患者SF-36量表评分结果与合并HIV感染与否、年龄、家庭关系、经济收入、梅毒分期、规范治疗、心理因素比较,差异有统计学意义(P<0.05),文化程度、防治知识、锻炼、居住地不同对患者SF-36评分结果无影响;60.54%的隐性梅毒患者存在不同程度的抑郁心理,梅毒分期与SDS量表评分结果呈正相关(P<0.05)。结论在影响梅毒患者生活质量的因素中,合并HIV感染与否、年龄、家庭关系、经济收入、梅毒分期、规范治疗、心理因素与患者生活质量密切相关,其中合并HIV感染影响最大,大部分隐性梅毒患者存在不同程度的抑郁。因此,在临床防治梅毒、改善患者生活质量时应进行有针对性的诊治和心理支持。

Objective To investigate the influencing factors of quality of life in patients with syphilis in northern Guangxi.Methods A total of 370 patients with syphilis who were diagnosed and treated in our hospital from January 2015 to January 2018 were analyzed.The clinical data,SF-36 scale and SDS scale scores were analyzed.Parallel multivariate stepwise linear regression analysis was used to analyze the influence factors of SF-36.Results The SF-36 scale scores of syphilis patients were significantly different among those of HIV infection,age,family relationship,economic income,syphilis stage,standardized treatment,and psychological factors(P<0.05).The degree of education,prevention knowledge,exercise,and place of residence had no effect on the SF-36 scores of patients.Patients(60.54%) with recessive syphilis had different degrees of depression,and the syphilis stage was positively correlated with the SDS scale(P<0.05).Conclusion Among the factors affecting the quality of life of patients with syphilis,the combination of HIV infection,age,family relationship,economic income,syphilis staging,standard treatment,psychological factors are closely related to the quality of life of patients.Patients with syphilis have varying degrees of depression.Therefore,in the clinical prevention and treatment of syphilis,the improvement of the quality of life of patients should contain the targeted personalized treatment and psychological support.