术前口服用药对不可逆性牙髓炎患者下牙槽神经阻滞影响的研究

The effect of preoperative oral medication on the effect of inferior alveolar nerve block in patients with irreversible pulpitis

纳入汉中市中心医院口腔科150例不可逆性牙髓炎患者,采用VAS评分后,将患者随机分为3组(n=50),分别口服酮咯酸片(KETO组),双氯芬酸钾片(DP组),纤维素粉片剂(placebo组), 3组均服药后1 h给予2%的含1∶200 000肾上腺素的利多卡因行下牙槽神经阻滞(IANB)。IANB注射成功采用冷试验进行评估,患者牙髓麻醉的成功率以牙髓治疗时患者痛觉判定。结果表明:3组患者年龄、性别及服药前VAS评分无显著性差异(P>0.05),所有患者术后疼痛评分较术前均显著降低(P<0.0001)。VAS评分顺序为,KETO组< DP组< placebo组(P <0. 000 1 )。3组IANB牙髓麻醉成功率KETO组78%, DP组56%,placebo组28%(P<0.05)。

150 patients with irreversible pulpitis were included and randomly divided into 3 groups(n=50) and treated with oral tablets of ketorolac(KETO), diclofenac pottasium(DP) and cellulose powder(placebo) respectively 1 h prior to administration of inferior alveolarnerve block(IANB) with 2% lidocaine containing 1 ∶200 000 epinephrine. Lip numbness and cold test were used for the determination of IANB injection success. The pain related to dental pulp treatment was used as the failure of IANB for pulp anesthesia. Bere treatment no significant difference of age, gender and VAS score was found among the 3 groups(P>0.05). Patients of all the 3 groups reported a significant decrease in active pain after IANB(P<0.000 1). The order of VAS values was KETO<DP<placebo(P<0.000 1). The success rate of pulp anesthesia by IANB of group KETO, DP and placebo was 78%, 56% and 28% respectively(P<0.05).