脑卒中便秘患者中医护理干预效果Meta分析

Meta-Analysis of the Effect of TCM Nursing Intervention for Post-Stroke Constipation Patients

目的:评价中医护理对脑卒中便秘患者的干预效果。方法:通过计算机检索多个中英文数据库,搜索符合纳入及排除标准的随机对照实验,评价纳入的文献质量后,采用RevMan5.3进行数据分析。结果:共纳入10个随机对照实验,Meta分析结果显示:7项研究将有效率作为评价指标,中医护理干预组有效率明显高于对照组,合并效应具有统计学意义[OR=3.87,95%CI(2.43,6.17),P<0.01];5项研究将便秘发生率作为评价指标,中医护理干预组便秘发生率明显低于对照组,合并效应具有统计学意义[OR=0.23,95%CI(0.13,0.42),P<0.01];4项研究将护理满意度作为评价指标,其中有2项研究由于使用的护理满意度评估工具不同,无法提取数据后进行Meta分析,另2项研究进行Meta分析后显示中医护理干预组患者的护理满意度高于对照组,合并效应具有统计学意义[OR=8.63,CI(3.11,23.90),P<0.01]。结论:中医护理干预脑卒中便秘患者的临床疗效优于对照组。但由于纳入分析的研究较少,整体质量偏低,需要开展更多大样本、高质量的临床研究,来进一步证实中医护理干预对脑卒中便秘患者的疗效。

Objective: To evaluate the effect of TCM nursing intervention for post-stroke constipation. Methods: Randomized clinical trials(RCTs) that assessed the effect of TCM nursing intervention for post-stroke constipation were selected in multiple electronic databases. RevMan5.3 software was used to analyze the data after quality assessment, and data extraction were made for eligible RCTs. Results: A total of 10 RCTs were included. Meta-analysis results showed that 7 studies regarded efficiency as an evaluation index, and the effective rate of TCM nursing intervention group was significantly higher than that of control group [OR=3.87,95% CI(2.43,6.17), P<0.01].Five studies regarded the incidence of constipation as an evaluation index, and the incidence of constipation in TCM nursing intervention group was significantly lower than that in control group [OR=0.23,95%CI(0.13,0.42), P<0.01]. The 5 studies regarded nursing satisfaction as an evaluation index, and two of the studies were unable to extract data for meta-analysis because the different nursing satisfaction assessment tools were used. The other 2 studies conducted meta-analysis showed that the nursing satisfaction of TCM nursing intervention group was higher than that of the control group [OR=8.63,95%CI(3.11,23.90), P<0.01]. Conclusion: The effect of TCM nursing intervention for post-stroke constipation is better than that of the control group. However, due to fewer studies included in the analysis and the overall quality is low. The more large samples and high-quality clinical research are needed to further confirm the efficacy of TCM nursing intervention on stroke patients with constipation.