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新斯的明拮抗顺式阿曲库铵对老年患者术后恢复的影响 被引量:3

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摘要 目的观察新斯的明拮抗顺式阿曲库铵对老年患者术后麻醉恢复室(PACU)中恢复情况和呼吸系统感染事件发生的影响。方法 400例拟行腹腔镜手术(外科、泌尿科和妇科)的患者分为2组,每组200例。在PACU中分别给予新斯的明40 μg/kg和阿托品5 μg/kg(拮抗组)或5 ml生理盐水(安慰剂组)。记录:⑴达到《最低PACU出室标准》时间和TOFR;⑵术后不良反应发生率包括术后24 h低氧血症、术后恶心呕吐和疼痛需治疗以及术后30 d因呼吸系统不良反应就医的发生率;⑶术后住院时间和住院总费用。结果拮抗组达到《最低PACU出室标准》时间明显缩短,此时TOFR也明显高于安慰剂组(P<0.05)。两组术后24 h低氧血症、术后恶心呕吐和疼痛需治疗、术后30 d因呼吸系统不良反应就医的发生率、术后住院时间和住院总费用比较差异无统计学意义(P>0.05)。结论小剂量新斯的明拮抗顺式阿曲库铵能缩短老年患者恢复室使用时间,不增加患者住院时间、住院总费用和术后呼吸系统感染事件的发生。
出处 《中国医师杂志》 CAS 2019年第5期730-733,共4页 Journal of Chinese Physician
基金 上海黄浦区科研项目计划(HKW201604)
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