右美托咪定联合舒芬太尼对三叉神经痛患者术后镇痛效果观察

Effect of Dexmedetomidine Combined with Sufentanil on Postoperative Analgesia in Patients with Trigeminal Neuralgia

目的观察右美托咪定联合舒芬太尼对三叉神经痛(TN)患者术后镇痛效果。方法选取我院2015年1月-2017年1月收治的60例择期行TN手术患者为对象,采用随机数字法将其分为对照组和实验组各30例,对照组术后给予舒芬太尼进行镇痛,实验组在对照组的基础上给予右美托咪定进行镇痛。比较两组镇痛效果及不良发应。结果实验组术后6h、12h、24h及48h的VAS评分均显著于对照组(P<0.05);实验组总并发症发生率为5.00%显著低于对照组的18.33%(P<0.05)。结论右美托咪定联合舒芬太尼对TN患者术后镇痛疗效显著,且安全性较高,值得进一步推广使用。

Objective To observe the effect of dexmedetomidine combined with sufentanil on postoperative analgesia in patients with trigeminal neuralgia(TN).Methods 60 patients undergoing elective TN surgery in the hospital from January 2015 to January 2017 were enrolled.They were divided into control group and experiment group by random number table method,30 cases in each group.The control group was given sufentanil for analgesia after surgery.On this basis,the experiment group was additionally given dexmedetomidine for analgesia.The analgesic effect and adverse reactions were compared between the two groups.Results The VAS scores of the experiment group at 6h,12h,24h and 48h after surgery were significantly higher than those of the control group(P<0.05).The total incidence of complication in the experiment group was significantly lower than that in the control group(5.00%vs 18.33%)(P<0.05).Conclusion The curative effect of dexmedetomidine combined with sufentanil is significant on postoperative analgesia in TN patients,with relatively higher safety.Which is worthy of further promotion.