硫酸镁联合硝苯地平在妊娠高血压治疗中的临床效果研究

Clinical Effect of Magnesium Sulfate combined with Nifedipine in the Treatment of Pregnancy Induced Hypertension

目的研究硫酸镁联合硝苯地平给药相比单纯硫酸镁注射在妊娠高血压患者治疗中的临床效果差异。方法将2012年6月至2017年6月本院的106例妊娠高血压患者,随机分为对照组以及联合组。对照组25%硫酸镁溶液以及500 mL的5%葡萄糖溶液静脉滴注,联合组在接受同样的滴注的基础下,给予硝苯地平控释片,进行血压调节情况、检测指标变化情况以及治疗有效率比较。结果治疗效果方面,联合组总有效率为92.5%,对照组为75.5%,明显高于对照组(P<0.05)。结论联合组治疗方案能更加明显的提高妊娠高血压患者多项临床症状,具有较强的推广价值。

Objective To study the clinical effect of magnesium sulfate combined with nifedipine in the treatment of patients with pregnancy induced hypertension.Methods From June 2012 to June 2017,106 patients with pregnancy-induced hypertension were randomly divided into control group and combined group.Patients in the control group received 50 mL of 25%magnesium sulfate solution and 500 mL of 5%glucose solution intravenously every day.The combined group received 2 drops of nifedipine control tablets,30 mg each time,on the basis of the same infusion.Blood pressure regulation,changes in detection indicators and treatment efficiency.Results The total effective rate was 92.5%in the combined group and 75.5%in the control group,which was significantly higher than that in the control group(P<0.05).Conclusion The combined treatment regimen can improve the clinical symptoms of patients with pregnancy induced hypertension and have a strong promotion value.