心脏康复对慢性心力衰竭患者心功能改善与生活质量的影响分析

Effect of Cardiac Rehabilitation on Heart Function Improvement and Quality of Life in Patients with Chronic Heart Failure

目的探讨心脏康复治疗对慢性心力衰竭患者心脏功能改善与生活质量影响。方法选择2016年1月至2018年6月诊断慢性心力衰竭(NYHAⅠ~Ⅱ级)患者150例,随机分为康复组与对照组,各75例。对照组患者依据其危险因素给予常规药物治疗。康复组在对照组治疗基础上给予心脏康复治疗,治疗时间6个月。治疗前后,采用免疫化学法检测两组患者血浆氨基末端脑钠尿肽(NT-proBNP)、血清肌钙蛋白I(cTnI),测量心脏超声参数左心房内径(LAD)、左室舒张末期内径(LVEDd)、射血分数及E/A比值变化差异,比较两组患者6 min步行距离,采用SF-36心力衰竭量表评估患者生活质量差异。结果治疗后,两组患者血浆NT-proBNP、血清cTnI水平下降,LAD、LVEDd缩小,EF、E/A比值升高,治疗前后比较差异无统计学意义(P<0.05)。其中,康复组改善幅度优于对照组(P<0.05)。治疗后,康复组患者6 min步行距离与生活质量显著改善,两组比较差异有统计学意义(P<0.05)。结论心脏康复治疗可以显著提高慢性心力衰竭患者心脏功能,防治心室重构,提高患者生活质量。

Objective To investigate the effect of cardiac rehabilitation therapy on the improvement of cardiac function and quality of life in patients with chronic heart failure.Methods 150 patients with chronic heart failure(NYHAⅠ-Ⅱ)diagnosed from January 2016 to June 2018 were randomly divided into rehabilitation group and control group,which were seventy-five cases in each group.Patients in the control group were given routine drug treatment according to their risk factors.The rehabilitation group was given cardiac rehabilitation treatment on the basis of the control group,and the treatment time was six months.Before and after treatment,plasma NT-proBNP and cTnI were detected by immunochemical method,left atrial diameter(LAD),left ventricular end-diastolic diameter(LVEDd),ejection fraction and E/A ratio were measured,and 6 minute walking distance was compared between the two groups.SF-36 Heart Failure Scale was used to evaluate the quality of life of patients.Results After treatment,the levels of NT-proBNP and cTnI decreased,LAD and LVEDd decreased,EF and E/A ratio increased in both groups,and there was no significant difference before and after treatment(P<0.05).Among them,the improvement of rehabilitation group was better than that of control group(P<0.05).After treatment,the 6 minute walking distance and quality of life in the rehabilitation group were significantly improved,and the difference between the two groups was statistically significant(P<0.05).Conclusion Cardiac rehabilitation therapy can significantly improve cardiac function,prevent ventricular remodeling and improve the quality of life of patients with chronic heart failure.