基于CRITIC法计算权重系数的枳壳综合品质研究

Quality Evaluation of Aurantti fructus Based on CRITIC Method

目的:测定不同产地枳壳有效成分含量并评价其质量,为其作为中药类保健食品原料开发利用提供理论基础。方法:采用高效液相色谱法、紫外分光光度法分别测定枳壳中柚皮苷、新橙皮苷、多酚、三萜及多糖的含量,并基于CRITIC客观赋值法进行综合评价。结果:样品中柚皮苷、新橙皮苷、多酚、三萜及多糖的质量分数分别为44.78~131.39、21.14~74.17、33.38~71.90、7.80~19.50、0.75~1.81mg·g^-1。由加权得分可知,样品编号为AF-7的综合评分最高,品质最佳,其次是AF-10;AF-4的得分最低,各项指标数值低,质量较差。结论:不同产地枳壳有效成分含量差异较大,通过多指标成分分析综合客观评价了枳壳的品质,以沅江三眼塘产区枳壳综合评分最佳、质量最优,体现了湘枳壳的道地性,为今后其作为保健食品的开发利用提供参考。

Objective:This paper focused on analyzing the content of effective components in Aurantti fructus from different regions,and evaluating their qualities.Then the theoretical basis was provided for the explotation and utilization of A.fructus,as a health food raw material.Methods:The content of naringin and neohesperidin was determined by HPLC,and the level of polyphenols,triterpenoids and polysaccharides was determined by UV spectrophotometry.The comprehensive evaluation was based on the method of Criteria Importance Through Inter-criteria Correlation(C RITIC).Results:The content ranges of these components in samples were 44.78-131.39,21.14-74.17,33.38-71.90,7.80-19.50 and 0.75-1.81 mg·g^-1,respectively.It is concluded from the weighted scores that AF-7 has the highest comprehensive score and the best quality,followed by AF-10.Among the 12 samples,AF-4 scored lowest with the low content of effective fractions and poor quality.Conclusion:The content of effective compositions in A.fructus has significant differences.The quality of these samples was evaluated through multi-indicator analysis,and the samples from Sanyantang of Yuanjiang have higher scores and better qualities,which represents strongly the geo-herbalism of the Hunan A.fructus.It can provides references for the further development of health food from A.fructus.