联用盐酸羟考酮与盐酸曲马多对进行剖宫产手术后的产妇实施静脉自控镇痛的效果

Effect of oxycodone hydrochloride and tramadol hydrochloride for patient-controlled intravenous analgesia to the puerperal in caesarean process

目的 :探讨联用盐酸羟考酮与盐酸曲马多对进行剖宫产手术后的产妇实施静脉自控镇痛的效果。方法 :选取2017年11月至2018年3月期间在成都双楠医院进行剖宫产手术的80例产妇作为研究对象。将这些产妇平均分为试验组和对照组。进行剖宫产手术后,均为这些产妇注射盐酸托烷司琼。在此基础上,用30 mg的盐酸羟考酮和500 mg的盐酸曲马多对试验组产妇进行静脉自控镇痛,用100μg的枸橼酸舒芬太尼和500mg的盐酸曲马多对对照组产妇进行静脉自控镇痛。然后比较两组产妇镇痛的效果。结果 :在手术后6h、12h、24h、48h,试验组产妇切口VAS评分、宫缩VAS评分均低于对照组产妇(P <0.05)。在手术后6h、12h,试验组产妇按压自控镇痛泵的次数均少于对照组产妇(P <0.05)。试验组产妇不良反应的发生率低于对照组产妇,但二者相比,P>0.05。结论 :联用盐酸羟考酮与盐酸曲马多对进行剖宫产手术后的产妇实施静脉自控镇痛的效果较为理想,安全性较高。

objective: to investigate the effect of combined administration of oxycodone hydrochloride and tramadol hydrochloride on parturient patients with controlled intravenous analgesia after cesarean section. Methods: 80 parturients who underwent cesarean section in chengdu shuangnan hospital from November 2017 to March 2018 were selected as research objects. The women were equally divided into a trial group and a control group. After cesarean section, these women were injected with toransetron hydrochloride. On this basis, 30 mg of oxycodone hydrochloride and 500 mg of tramadol hydrochloride were used for pca in the experimental group,and 100 g of sufentanil citrate and 500 mg of tramadol hydrochloride were used for pca in the control group. Then compare the analgesic effect between the two groups.Results: at 6 h, 12 h, 24 h and 48 h after surgery, the incision VAS score and uterine VAS score of the experimental group were lower than those of the control group(P< 0.05). At 6 h and 12 h after surgery, the number of pca pump presses in the experimental group was less than that in the control group(P < 0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group, but P > was 0.05. Conclusion: combined administration of oxycodone hydrochloride and tramadol hydrochloride is effective and safe in parturient women undergoing cesarean section.