前降支肌桥与桥前血管动脉粥样硬化狭窄的相关性

Correlation between myocardial bridge(MB) of anterior descending branch coronary artery and atherosclerotic stenosis in the segment proximal to the site of bridge

目的探讨前降支肌桥与桥前血管动脉粥样硬化狭窄的相关性,以明确前降支肌桥是否可作为桥前血管动脉粥样硬化狭窄的独立危险因素。方法统计436例前降支肌桥患者的临床资料,对前降支心肌桥前血管狭窄危险因素,如年龄、性别、高血压、2型糖尿病、高脂血症、吸烟史、家族史、心肌桥收缩期狭窄程度与桥前血管动脉粥样硬化狭窄之间的关系采用Logistic回归分析。结果前降支中段肌桥与桥前血管狭窄显著相关;年龄、高血压、2型糖尿病、吸烟史、心肌桥收缩期狭窄NobleⅡ-Ⅲ度与前降支桥前血管狭窄存在显著相关性(P<0.05);经过性别、年龄、高血压、糖尿病、高脂血症、吸烟史、家族史等因素校正后,收缩期狭窄NobleⅡ-Ⅲ度(OR=1.98,95%CI:0.06~1.37)与前降支桥前血管狭窄存在较强相关性。结论前降支中段肌桥收缩期狭窄NobleⅡ-Ⅲ度可作为前降支桥前血管狭窄的独立危险因素。

Objective To investigate the correlation between myocardial bridge (MB) of anterior descending branch coronary artery and atherosclerotic stenosis in the segment proximal to the site of bridge,and to determine whether MB of anterior descending branch coronary artery can be taken as an independent risk factor of atherosclerotic stenosis in the segment proximal to the site of bridge. Methods The clinical data was counted from 436 patients with MB of anterior descending branch coronary artery. The relationship between the risk factors related to atherosclerotic stenosis in the segment proximal to the site of bridge,including age,sex,hypertension, type 2 diabetes mellitus (T2DM),hyperlipidemia,smoking history,family history and MB systolic stenosis severity and atherosclerotic in the segment proximal to the site of bridge was analyzed by using Logistic regression analysis. Results The MB in the middle segment of anterior descending branch artery was significantly correlated to atherosclerotic stenosis in the segment proximal to the site of bridge. Age,hypertension,T2DM,smoking history,Noble grade Ⅱ and Noble grade Ⅲ systolic stenosis of MB were significantly correlated to atherosclerotic stenosis in the segment proximal to the site of bridge (P<0.05). After correcting sex,age,hypertension,diabetes, hyperlipidemia,smoking history and family history,Noble grade Ⅱ and Noble grade Ⅲ systolic stenosis of MB was correlated to atherosclerotic stenosis in the segment proximal to the site of bridge (OR=1.98,95%CI:0.06~1.37). Conclusion Noble grade Ⅱ and Noble grade Ⅲ systolic stenosis of MB in middle segment of anterior descending branch coronary artery can be taken as an independent risk factor of atherosclerotic stenosis in the segment proximal to the site of bridge of anterior descending branch coronary artery.