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急性心肌梗死患者PCI术前血小板参数、NLR与院内MACE发生的关系 被引量:16

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摘要 目的分析急性心肌梗死(AMI)患者经皮冠状动脉介入(PCI)术前血小板参数[(血小板平均体积(MPV)、血小板分布宽度(PDW)]、中性粒细胞/淋巴细胞(NLR)与院内主要不良心血管事件(MACE)发生的关系。方法选择急诊行PCI的AMI患者480例,根据是否发生MACE分为发生者与未发生者,比较两者术前MPV、PDW、NLR,应用多因素Logistic回归分析分析AMI患者发生MACE的危险因素。绘制MPV、PDW、NLR预测MACE发生的受试者工作特征(ROC)曲线。结果480例AMI患者中,56例发生院内MACE。MACE发生者较未发生者NLR、MPV、PDW高(P均<0.01)。Logistic回归分析结果显示,PCI术前高NLR(OR=20.431,95%CI:6.794~70.168,P<0.05)、高MPV(OR=1.593,95%CI:1.075~5.169,P<0.05)、高PDW(OR=2.049,95%CI:0.846~9.082,P<0.05)是AMI患者发生院内MACE的独立危险因素。ROC曲线分析结果显示,NLR、MPV、PDW预测院内MACE发生的ROC曲线下面积分别为0.848、0.782、0.709。结论AMI患者PCI术前MPV、PDW、NLR与院内MACE发生有关,三者水平升高可在一定程度上预测院内MACE发生。
作者 贾伟 蔺小艳
机构地区 榆林市第二医院
出处 《山东医药》 CAS 2019年第16期66-68,共3页 Shandong Medical Journal
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