摘要
艰难梭菌是一种革兰阳性厌氧芽孢杆菌,现已成为全球分布的主要肠道病原体。艰难梭菌感染(Clostridium dif ficile infection,CDI)可引起抗菌药物相关性腹泻,而其严重感染会导致假膜性结肠炎和中毒性巨结肠等严重并发症。CDI正成为全世界公共卫生的一个持续挑战。本文就近年来国内外CDI的诊断、预防和治疗予以简要综述,为防治CDI提供依据。
Clostridium difficile (C. difficile) is a gram-positive anaerobic bacillus and has become a major intestinal pathogen worldwide. C. difficile infection (CDI) can cause antimicrobial-associated diarrhea, severe infection may lead to severe complications such as pseudomembranous colitis and toxic megacolon. CDI is becoming a continuing challenge to public health worldwide. In this paper, the diagnosis, prevention and treatment of CDI at home and abroad in recent years are briefly reviewed, so as to provide a basis for the prevention and treatment of CDI.
作者
季欣欣
孟秀娟(综述)
任南
黄勇(审校)
JI Xin-xin;MENG Xiu-juan;REN Nan;HUANG Yong(Xiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China;Center for Healthcare-associated Infection Control, Xiangya Hospital, Central South University, Changsha 410008, China;National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery, Changsha 410205, China)
出处
《中国感染控制杂志》
CAS
CSCD
北大核心
2019年第6期600-606,共7页
Chinese Journal of Infection Control
基金
国家自然科学基金面上项目(81473123)
关键词
艰难梭菌
毒素
感染
危险因素
肠道菌群
Clostridium difficile
toxin
infection
risk factor
intestinal flora
