小剂量甘露醇治疗老年急性大面积脑梗塞70例临床研究

Clinical Study of 70 Cases of Acute Large-area Cerebral Infarction Treated with Low-dose Mannitol

目的探讨小剂量甘露醇治疗老年急性大面积脑梗塞的临床疗效。方法方便选取2017年1月—2018年6月收治的老年急性大面积脑梗塞患者70例,随机分为观察组和对照组,每组35例,对照组使用大剂量甘露醇治疗,观察组使用小剂量甘露醇治疗,对比两组治疗效果。结果观察组总有效率60.0%,对照组总有效率62.9%(χ^2=0.060,P=0.806)。结论小剂量甘露醇治疗老年急性大面积脑梗塞效果良好,值得推广应用。

Objective To investigate the clinical efficacy of low-dose mannitol in the treatment of acute large-area cerebral infarction in the elderly. Methods Seventy elderly patients with acute large-area cerebral infarction admitted from January 2017 to June 2018 were convenient divided into observation group and control group, 35 cases in each group. The control group was treated with large dose of mannitol, and the observation group with small dose of mannitol, compared the effects of the two groups. Results The total effective rate of the observation group was 60.0%, and the total effective rate of the control group was 62.9%(χ^2=0.060, P=0.806). Conclusion Low-dose mannitol is effective in the treatment of acute large-area cerebral infarction in the elderly. It is worthy of popularization and application.