急性缺血性脑卒中急性期血压控制水平对患者近期预后的改善作用临床分析

Clinical Observation and Analysis of the Effect of Blood Pressure Control in Acute Phase of Acute Ischemic Stroke on Patients with Short-term Prognosis

目的探讨急性缺血性脑卒中急性期血压控制水平对患者近期预后的改善作用临床观察。方法方便选自该院2017年1月—2018年12月期间治疗的150例急性缺血性脑卒中患者,按照随机将150例患者等分为研究1组、研究2组和对比组,各50例,研究1组急性期血压控制在120/80mmHg,研究2组血压控制在140/90mmHg,对比组不实施血压控制,对3组患者脑卒中评分进行对比分析,观察比较3组患者近期预后的改善效果。结果治疗3、7、14d后研究1组、研究2组脑卒中评分分别为(8.52±2.39)分、(6.64±2.27)分、(6.26±3.10)分、vs(8.26±2.18)分、(6.33±2.15)分、(6.22±2.89)分,明显低于对比组3、7、14d脑卒中评分(9.25±3.53)分、(8.31±3.25)分、(7.96±3.21)分,组间差异有统计学意义(P<0.05);从临床治疗效果比较,研究2组近期临床有效率高达92.00%,研究1组和对比组近期临床有效率分别为88.00%和64.00%,研究1组和研究2组近期临床有效率明显高于对比组,差异有统计学意义(χ^2=7.3842,P=0.0001),但研究1组和研究2组之间差异无统计学意义(χ^2=1.0126,P=0.4369)。结论急性缺血性脑卒中急性期血压控制水平对患者近期预后效果显著,有助于促进患者尽早恢复神经功能,提高临床治愈率,值得在临床中推广应用。

Objective To investigate the effect of blood pressure control in acute phase of acute ischemic stroke on the improvement of short-term prognosis in patients. Methods 150 patients with acute ischemic stroke treated in our hospital from January 2017 to December 2018 were convenient selected. According to randomization, 150 patients were divided into study group 1, study group 2 and control group, 50 cases each. The blood pressure of the acute blood pressure control group was 120/80mmHg, the blood pressure of the two groups was controlled at 140/90mmHg, the blood pressure control was not performed in the control group, and the stroke scores of the three groups were compared. The short-term prognosis of the three groups was compared. Results After 3 d, 7 d, and 14 d, the stroke scores of study group 1 and study group 2 were (8.52±2.39)points,(6.64±2.27)points,(6.26±3.10)points vs (8.26±2.18)points,(6.33±2.15)points,(6.22±2.89)points, and the stroke scores (9.25±3.53)points,(8.31±3.25)points, and (7.96±3.21)points were significantly lower than those of the control group at 3 d, 7 d, and 14d. The difference between the groups was statistically significant (P<0.05). From the comparison of clinical treatment effects, the recent clinical effective rate of the two groups was as high as 92.00%. Study group 1 and control group of recent clinical effective rates were 88.00% and 64.00%, respectively. The clinical efficacy of the study group 1 and the study group 2 was significantly higher than that of the control group. The difference was statistically significant (X^2=7.384 2, P=0.000 1), but the study group 1 had no significant difference from the study group 2 (X^2=1.012 6, P=0.436 9). Conclusion The blood pressure control level of acute ischemic stroke has a significant effect on the short-term prognosis of patients, which is helpful to promote the early recovery of neurological function and improve the clinical cure rate. It is worthy of popularization and application in clinic.