卡维地洛联合胺碘酮治疗心律失常的近期应用效果及有效率影响评价

The Short-term Application Effect and Effective Evaluation of Carvedilol Combined with Amiodarone in the Treatment of Arrhythmia

目的观察卡维地洛联合胺碘酮治疗心律失常的近期应用效果及有效率影响。方法选定该院2016年1月—2018年7月间收治的心律失常62例,分组原则以入院顺序奇偶性为主,分对照组(31例,采取胺碘酮治疗)、试验组(31例,在对照组基础上联合卡维地洛治疗),比较近期临床疗效、左心室射血分数和平均心率。结果试验组临床近期总有效率(93.54%)显著较对照组(74.19%)高,(χ^2=4.292,P<0.05);治疗前1d,试验组左心室射血分数(LVEF)、平均心率与对照组相比差异无统计学意义(P>0.05),治疗2周后,两组患者上述指标改善,且试验组LVEF(57.65±3.86)%更高,平均心率(82.11±3.64)次/min更低(t=9.322、10.086,P<0.05)。结论在心律失常治疗中,胺碘酮治疗基础上联合卡维地洛治疗近期效果理想,较胺碘酮单纯治疗更为突出,利于患者病情恢复,值得借鉴。

Objective To observe the short-term effect and effective effect of carvedilol combined with amiodarone in the treatment of arrhythmia.Methods 62 cases of arrhythmia admitted to our hospital were selected.The study period was from January 2016 to July 2018.The grouping principle was based on the parity of admission order.The control group (31 cases,treated with amiodarone),The experimental group (31 patients,combined with carvedilol on the basis of the control group),compared the recent clinical efficacy,left ventricular ejection fraction and average heart rate.Results The total clinical effective rate (93.54%) of the experimental group was significantly higher than that of the control group (74.19%)(χ^2=4.292,P<0.05);1d before treatment,the left ventricular ejection fraction (LVEF),average of the experimental group The heart rate was different from the control group,but the difference was not statistically significant(P>0.05).After 2 weeks of treatment,the above indicators improved in both groups,and the test group had higher LVEF (57.65±3.86)% and average heart rate (82.11±3.64) Times/min was lower(t=9.322,10.086,P<0.05).Conclusion In the treatment of arrhythmia,amiodarone treatment combined with carvedilol has a short-term effect,which is more prominent than amiodarone alone,which is beneficial to the recovery of patients' condition and worth learning.