31858例住院患者不规则抗体筛查及抗体鉴定结果分析

Analysis of irregular antibody screening and antibody identification results in 31858 cases of inpatients

目的分析31 858例住院患者不规则抗体筛查及抗体鉴定结果,探究其对安全输血的临床意义。方法采用微柱凝胶检测卡对31 858例住院患者进行不规则抗体筛查及抗体鉴定。结果 31 858例住院患者中, RhD阳性患者31 517例(98.92%), RhD阴性患者341例(1.08%)。抗体筛查阳性患者92例,阳性率0.3%,血液病患者抗筛阳性检出率最高为2.21%(11/497),妊娠孕妇抗筛阳性率为0.72%(31/4313)。92例不规则抗体鉴定结果为:抗E 45例(48.91%)、抗D 11例(11.96%)、抗c 10例(10.87%)、抗Le^a 6例(6.52%)、抗Ec 5例(5.44%)、抗M 5例(5.44%),其他抗体10例。结论输血前进行抗体筛查与抗体鉴定,可有效避免输血不良反应的发生,提高输血质量。

Objective To explore clinical significance of transfusion safety by analyzing the results of screening the irregular antibodies and antibody identification. Methods The micro-column gel test cards were used to screen and identify irregular antibodies of 31 858 inpatients. Results Among the 31 858 cases, 31 517(98.92%) had positive results in RhD detection, and 341(1.08%) had negative results in RhD detection. The number of patients who had positive results in screening the irregular antibodies was 92 cases and the positive rate was 0.3%. The highest detected rate of positive results in screening the irregular antibodies was obtained in the patients with hematologic diseases at a rate of 2.21%(11/497), closely followed by the pregnant women at a rate of 0.72%(31/4313). The 92 cases had positive results in antibody identification, including 45 cases of anti-E(48.91%), 11 cases of anti-D(11.96%), 10 cases of anti-c(10.87%), 6 cases of anti-Le^a(6.52%), 5 cases of anti-Ec(5.44%), 5 cases of anti-M(5.44%), and 10 cases of other antibodies. ConclusionScreening the irregular antibodies and antibody identification before blood transfusion can effectively avoid the adverse reactions of blood transfusion and improve the quality of blood transfusion.