急性主动脉夹层国际注册数据库结果比较分析

Large clinical registries for acute aortic dissection: interpretation and comparison of latest results

过去60年内,尽管急性主动脉夹层的诊断治疗技术有了巨大进步,其死亡率和并发症发生率仍居高不下。由于发病率相对较低,为了通过收集大样本患者资料提高对该病的认识,国际同行建立了数个临床注册数据库,包括急性主动脉夹层国际注册数据库(IRAD)、德国急性A型主动脉夹层注册数据库(GERAADA)和美国胸外科医师协会(STS)成人心脏外科数据库主动脉分库。本文根据IRAD、GERAADA和STS主动脉数据库的最新结果,针对部分热点问题进行探讨和对比,为国内心血管专业同道提高急性主动脉夹层的诊断治疗水平提供借鉴参考。

Despite the improvements in the diagnosis and management during the past six decades, acute aortic dissection (AAD) remains a life-threatening condition associated with significant morbidity and mortality rates. Due to the relatively rare occurrence of AAD, several clinical registries have been established to gain insights into this lethal disease in a large number of patients, such as the International Registry of Acute Aortic Dissection (IRAD), the German Registry for Acute Aortic Dissection Type A (GERAADA), and the Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database Aortic Section. This review aims to interpret and compare the latest results of the IRAD, STS and GERAADA database. It focuses on several controversial and key issues in the diagnosis and management of acute aortic dissection in hope of providing some insights and references for cardiovascular professionals engaged in the care of this deadly disease.