27重SNP种族推断体系在案件中的应用

Application of 27-plex SNP Race Inference Assay into Tracing a Suspect’s Ethnogenesis: Case Report

应用公安部物证鉴定中心研发的27重SNP种族推断体系,对一起爆炸案件现场的检材进行种族来源推断,成功获得了该现场检材DNA的种族信息,其属混合人种,具有82%欧洲成分和11%东亚成分。该案循此侦查,查找到了嫌疑人的重要线索。本案所用推断体系可在常规DNA实验室应用,无需特殊仪器设备,可操作性强,所需DNA量小,适用于大部分检材。针对有些案件现场生物检材STR分型未能比中嫌疑人,使用该体系进行种族推断,可进一步挖掘现场检材蕴含的遗传信息,刻画嫌疑人,缩小侦查排查范围,为案件定性提供依据。

The 27-plex SNP race inference assay,developed by Institute of Forensic Science affiliated under Ministry of Public Security of the People’s Republic of China,was used to infer a suspect’s ethnogenesis,thus reaping the clue to have an involved case solved.One DNA sample,left at an explosion crime scene,turned out that it was an admixture consisting its ancestral components of 82% the European’s and 11% the East-Asian’s when tested by the above assay.Such an inference assay is able to perform in one ordinary forensic DNA laboratory,having merits of convenient operation,minor quantity of sample,wide spectrum of applicable specimens and no requirements of special instruments.For those biological samples whose STR genotypes fail to match,the race inference could be further mining the genetic information,depicting the suspect,narrowing the scope of investigation and therefore capable of providing the basis for case determination.