CDK1与结直肠癌的研究进展被引量：7

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摘要结直肠癌是全球常见肿瘤之一。早期结直肠癌患者5年生存率约90%,但晚期患者病死率明显升高。虽然治疗方法有了较大的进步,但其病死率仍较高。细胞周期蛋白依赖性激酶1(cyclin-dependent kinase 1,CDK1)是细胞周期的重要调控因素,与结直肠癌的发生、进展及预后密切相关。CDK1抑制剂有望成为结直肠癌治疗的新靶点。该文主要从CDK在有丝分裂中的作用和在肿瘤中的研究,以及与结直肠癌的研究进展作一综述。

作者艾平平谈顺

机构地区中南大学湘雅医学院附属海口医院病理科

出处《临床与实验病理学杂志》 CAS CSCD 北大核心 2019年第5期561-563,共3页 Chinese Journal of Clinical and Experimental Pathology

关键词结直肠肿瘤 CDK1 生存率靶点文献综述

分类号 R735.3 [医药卫生—肿瘤]

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参考文献1

1孙玉满,刘宏侠,杨俊泉,吴蒙.细胞周期依赖性蛋白激酶1(Cdk1/p34cdc2)对喉癌术后局部复发的预测价值[J].临床与实验病理学杂志,2015,31(3):293-298. 被引量：7

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