影响女性育龄期乳腺癌患者对生育能力受损风险认识及保留生育能力决策的因素

The Risk Awareness of Fertility Impairment and Decision Making of Fertility Retention in Female Breast Cancer Patients of Childbearing Age

目的评估育龄期乳腺癌患者对肿瘤综合治疗后生育能力损害的认知程度,分析影响患者保留生育能力决策的相关因素,帮助患者做出关于保留生育能力的合理决定。方法针对研究目的设计了相应的问卷调查表,对2016 年7 月至2018 年5 月在昆明医科大学第三附属医院乳腺外一科就诊的育龄期乳腺癌患者进行问卷调查。结果在平均年龄为36 岁的126 名患者中,有76.2%的患者在治疗前获得了生育能力受损风险的相关信息,但这类患者中只有5.6%选择在肿瘤治疗前保留生育能力。患者是否选择保留生育能力与其生育状况,文化程度有相关性,P<0.05,差异有统计学意义;与采取何种治疗方案差异无统计学意义(P> 0.05)。结论大部分育龄期女性乳腺癌患者在肿瘤综合治疗前接收到生育能力受损相关信息,但选择保留生育能力患者却极其有限。影响患者做出保留生育能力决策与与治疗方案无关,与生育状况、文化程度有关。

Objective To evaluate the recognition rate of fertility damage in breast cancer patients of childbearing age after comprehensive treatment of tumors, and to analyze the related factors that influence the decision of patients to retain fertility, so to help patients make sound decisions about preserving fertility. Methods A questionnaire survey was designed se rving the purpose of the study. Among breast cancer patients of childbearing age who were treated in the Department of Mammary Surgery of the Third Affiliated Hospital of Kunming Medical University from July 2016 to May 2018. Results Of the 126 patients with an average age of 36, 76.2% received information on the risk of impaired fertility before treatment, but only 5.6% of these patients chose to retain fertility before treatment. Whether the patients chose to retain fertility was related to their reproductive status, the degree of education( P < 0. 05),and the results showed statistical significance;whether the patients chose to retain fertility was not related to whatever the treatment plan was, which was not statistically significant(P > 0. 05).Conclusions The information on the fertility impairment of women with breast cancer in women of childbearing age has reached a relatively wide level before the comprehensive treatment of tumors, but the patients who choose to retain fertility are extremely few. The decision-making is influenced by the fertility status and education levels, but has nothing to do with the treatment plans.