茶多酚对动脉粥样硬化的预防作用与机理研究进展

Prevention of Tea Polyphenols on Atherosclerosis and Relative Mechanisms

动脉粥样硬化是多种心血管疾病的重要病理基础,对心脑血管的损害可累及全身各个器官。茶多酚能够通过抗炎、调节血脂水平、抑制 LDL 氧化修饰、改善内皮功能、保持斑块稳定性等不同途径有效预防动脉粥样硬化。本文就近年来茶多酚对动脉粥样硬化的预防功能与机理方面的研究进行综述。

Atherosclerosis is the pathological basis of many cardiovascular diseases. Its injury to the cardiovascular could cause damage to other organs. Numerous data had indicated that tea polyphenols have a good preventive effect on atherosclerosis, such as anti-inflammatory, regulating blood lipid levels, inhibiting LDL oxidation, improving endothelial function and maintaining the stability of atherosclerotic plaque. The aim of this article is to review the health benefits of tea polyphenols against atherosclerosis and to outline the molecular mechanisms of tea polyphenols in atherosclerosis prevention.