摘要
全膝关节置换术(TKA)后疼痛是影响患者满意度和住院时间的主要因素。目前临床实践指南建议采用多模式疼痛管理方案,包括使用局部麻醉、椎管内麻醉及周围神经阻滞等。关节周围注射在TKA后可提供满意的疼痛缓解。近年来布比卡因脂质体作为传统局部麻醉剂的长效替代物被引入,如布比卡因及罗哌卡因。布比卡因脂质体是一种缓释制剂,用于在最初应用后72h内提供局部止痛。关节周围注射布比卡因脂质体的疗效显著依赖于细致的注射技术。
Pain after total knee arthroplasty(TKA) is a major factor affecting patient satisfaction and length of hospital stay.Current clinical practice guidelines recommend a multimodal pain management program that includes local anesthesia,spinal anesthesia,and peripheral nerve block.Injection after TKA around the joint provides satisfactory pain relief.In recent years, bupivacaine liposomes have been introduced as long-acting alternatives to traditional local anesthetics,such as bupivacaine and ropivacaine.Bupivacaine liposomes are a sustained release formulation designed to provide local analgesia within 72 h of initial application.The efficacy of bupivacaine liposomes around the joints is significantly dependent on careful injection techniques.
作者
李航
王文波
LI Hang;WANG Wenbo(Department of Orthopedics,the First Affiliated Hospital of Harbin Medical University,Harbin150001,China)
出处
《医学综述》
2019年第10期2044-2048,共5页
Medical Recapitulate
关键词
全膝关节置换术
布比卡因脂质体
镇痛
术后疼痛
Total knee arthroplasty
Bupivacaineliposomes
Analgesia
Postoperative pain