SAP继发腹内感染临床微生物学研究

Clinical Microbiology of Severe Acute Pancreatitis Secondary Infection

目的:分析临床重症急性胰腺炎继发感染后细菌学特点。方法:采集2000年1月—2008年1月来源于天津市南开医院的符合重症急性胰腺炎标准的患者217例,统计分析符合重症急性胰腺炎,经腹腔渗液病原学培养及血培养阳性印证,继发腹内感染的42例患者的临床资料,分析继发感染后的微生物学特点。结果:继发感染主要发生在发病后2~3周内,时间主要集中在(17.30±1.95)d。感染患者中,革兰阴性合并革兰阳性菌感染23例,单纯革兰阴性菌感染13例,单纯革兰阳性菌感染4例,真菌感染2例。结论:继发感染多发生在发病后2~3周,时间主要集中在(17.30±1.95)d,以革兰阴性菌混合革兰阳性菌混合感染多见,菌株上以革兰阴性杆菌为主。

Objective To analyze the bacteriological characteristics of secondary infection of severe acute pancreatitis(SAP).Methods SAP patients(217 cases)in Tianjin Nankai Hospital from January 2000 to January 2008 according with the standard of SAP were collected,and the clinical information and bacteriological characteristics of 42 cases of secondary infection of SAP was analyzed.Results Secondary infection occurred mainly in 2–3 weeks after onset of SAP.Gram-negative bacteria merged with Gram-positive bacteria infection in 23 cases,only 13 cases were Gram-negative bacteria infection and 4 cases were Gram-positive bacteria infection,2 cases were fungal infection.Conclusion Secondary infection of SAP mainly occured in 2–3 weeks after onset.Gram-negative bacteria merged with Gram-positive bacteria infection can be often seen,Gram-negative bacilli is the main strain.