摘要
近年来介入医学发展已经成为独立于内科、外科之外的第三大治疗手段。镍钛合金材料作为一种性能优异的生物材料在微创介入领域得到越来越广泛的应用。本文简单介绍了镍钛形状记忆合金的特性,如形状记忆效应、超弹性、抗腐蚀性、耐磨性等。着重介绍了镍钛形状记忆合金在血管支架、封堵器、腔静脉滤器、心脏介入瓣膜以及腔道内植入支架等的应用和国产化情况,针对镍离子致癌性问题导致的镍钛合金产品临床使用的长期安全性展望了未来研究的发展方向。
With the development of invasive medical devices. Nitinol alloy has been widely used in clinical fields as a good biomaterial. The properties of nickel-titanium shape memory alloys were introduced briefly in this paper, such as shape memory effect, superelasticity, corrosion resistance and wear resistance. The application of nickel-titanium shape memory alloy in vascular stents, occlusion devices, vena cava filters, cardiac interventional valves, and stents in the lumens was highlighted. Future research direction was prospected to improve the long-term safety of nickel-titanium alloy.
作者
尹玉霞
王鲁宁
郝树斌
颜秉运
曹明昆
张海军
YIN Yuxia;WANG Luning;HAO Shubin;YAN Bingyun;CAO Mingkun;ZHANG Haijun(National United Engineering Laboratory for Biomedical Material Modification,Dezhou Shandong 251100,China;School of Materials Science and Engineering,University of Science and Technology,Beijing 100083,China;Shandong Quality Inspection Center for Medical Devices,Jinan Shandong 250101,China)
出处
《中国医疗设备》
2019年第6期153-156,共4页
China Medical Devices
基金
十二五国家科技支撑计划(2014BAI11B04)
