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阿德福韦酯治疗失代偿期乙肝肝硬化合并腹水患者的疗效观察 被引量:4

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摘要 目的分析阿德福韦酯治疗失代偿期乙肝肝硬化合并腹水患者的疗效。方法选取我院2016年3月-2018年3月收治的62例失代偿期乙肝肝硬化合并腹水患者,采取随机数字表法分为治疗组(31例)与对照组(31例)。对照组应用常规治疗,治疗组在对照组的基础上应用阿德福韦酯治疗,对比2组的治疗效果和安全性。结果治疗组患者治疗总有效率(93.5%)明显高于对照组(74.2%),天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、总胆红素(TBiL)明显低于对照组,白蛋白(ALB)明显高于对照组,HBeAg转阴率(54.8%)、HBV-DNA转阴率(45.2%)、ALT复常率(80.6%)明显高于对照组(29.0%,19.4%,54.8%),差异均有统计学意义(P<0.05)。结论对失代偿期乙肝肝硬化合并腹水患者应用阿德福韦酯治疗可取得显著疗效,且不良反应较少,值得在临床中推广应用。
作者 金秋菊
出处 《基层医学论坛》 2019年第19期2722-2724,共3页 The Medical Forum
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