艾斯西酞普兰治疗疱疹痛患者继发焦虑抑郁情绪的研究

Study on the escitalopram in the treatment of secondary anxiety and depression for the patients with postherpetic pain

目的对老年疱疹后疼痛继发焦虑抑郁情绪患者应用艾司西酞普兰后的疗效进行观察。方法应用汉密顿焦虑抑郁量表对两家医院60例带状疱疹疼痛伴有焦虑抑郁的患者进行评分。分为治疗组(常规治疗+抗焦虑抑郁剂——艾司西酞普兰)和对照组(仅常规治疗),于治疗前及治疗后第1、2、3、4周末进行疗效评定。结果治疗组较对照组的自觉症状缓解时间缩短,临床疗效明显。两组HAMD、HAMA评分差异均有显著性(P<0.05)。结论带状疱疹疼痛患者多存在焦虑抑郁情绪,而艾司西酞普兰能明显改善焦虑与抑郁情绪,可促进患者的早日康复。

Objective To observe the curative effect of escitalopram in the treatment of secondary anxiety and depression in the elderly patients with postherpetic pain.Methods 60 patients with postherpetic pain complicated with anxiety and depression in the two hospitals were scored using the Hamilton Anxiety and Depression Scale.They were divided into treatment group(conventional treatment+anti-anxiety depression agent-escitalopram)and control group(regular treatment only).Efficacy was assessed before treatment and at the end of week 1,week 2,week 3,and week 4 after treatment.Results The alleviation time for subjective symptoms was shorter in the treatment group than the control group,and the clinical effect was significant.There were significant differences in HAMD and HAMA scores between the two groups(P<0.05).Conclusion Patients with postherpetic pain often have anxiety and depression,and escitalopram can significantly improve anxiety and depression,and can promote the early recovery of patients.