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多西环素与阿奇霉素联用治疗宫颈支原体感染的效果观察 被引量:2

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摘要 目的探析宫颈支原体感染中联用多西环素与阿奇霉素的临床作用。方法 80例宫颈支原体感染患者,随机分为单一组和联用组,每组40例。两组均使用常规治疗,单一组在常规治疗基础上采用阿奇霉素治疗,联用组在单一组基础上采用盐酸多西环素片治疗。比较两组患者症状消失时间、治疗效果、副作用及复发情况。结果联用组患者的宫颈管外口黏膜消失时间(4.85±0.63)d、糜烂创面恢复时间(5.68±1.04)d均显著短于单一组的(7.46±0.95)、(7.96±0.92)d,差异均具有统计学意义(P<0.05)。联用组患者的治疗总有效率为95.00%(38/40),显著高于单一组的80.00%(32/40),差异具有统计学意义(P<0.05)。两组患者副作用发生率比较差异无统计学意义(χ^2=0.213, P=0.644>0.05);随访结束后,联用组患者的复发率显著低于单一组,差异具有统计学意义(χ^2=3.914, P=0.048<0.05)。结论宫颈支原体感染中联用多西环素与阿奇霉素可加快症状消失时间,改善治疗效果,减少复发,且不会明显增加副作用。
出处 《中国现代药物应用》 2019年第11期134-136,共3页 Chinese Journal of Modern Drug Application
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