颈静脉孔区副神经节瘤患者围术期心率血压的变化特征

Perioperative Influence of Jugulare Foramen Paraganglioma Resection on the Heart Rate and Blood Pressure

目的研究颈静脉孔区副神经节瘤切除术后患者心率和血压的变化特征。方法回顾性分析2015年7月至2019年3月收治并进行手术治疗的颈静脉孔区副节瘤患者18例。所有患者均行手术治疗,比较患者术前1周(基础值)与术后短期(1天、3天、7天)心率血压的变化。结果颈静脉孔区副节瘤患者术后1天、3天、7天心率(heart rate, HR)均增快,差异有统计学意义(P<0.01)。低剂量的β受体阻滞剂控制术后心率效果欠佳。住院期间心率恢复正常最长需21天。其它侧颅底肿瘤患者术后短期心率变化无统计学意义。颈静脉孔区副节瘤患者术后血压变化较其它侧颅底肿瘤无特异性。结论颈静脉孔区副节瘤切除后患者围术期心率有一定程度增快,此现象有一定的临床意义。

Objective To report effects of jugulare foramen paraganglioma resection on heart rate and blood pressure in the perioperative period. Methods Clinical data from 18 patients undergoing jugulare foramen paraganglioma resection from July 2015 to March 2019 was reviewed. Heart rate(HR) and blood pressure were recorded continuously during perioperative period. Results Heart rate increased for 1-7 days after operation(P<0.01). Low dose β-receptor blockers were not effective in controlling postoperative heart rate. In contrast, there were no significant changes in perioperative heart rate after other lateral skull base surgeries. It could take as long as 21 days for HR to fall down. There was no specific variation of blood pressure in these patients compared to other lateral skull base surgery patients. Conclusion Jugulare foramen paraganglioma resection is associated with postoperative heart rate increase. This finding is significant for perioperative management.