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辛伐他汀药理作用及临床应用效果观察 被引量:2

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摘要 目的:分析辛伐他汀药理作用及临床应用效果。方法:2017年8月-2018年6月收治老年慢性疾病患者92例,随机分为两组,各46例。均治疗合并的慢性基础疾病,对照组联合安慰剂,观察组联合辛伐他汀。对比两组各项指标。结果:观察组退出4例,对照组退出2例。两组治疗后收缩压(SBP)、舒张压(DBP)低于治疗前,差异有统计学意义(P<0.05);两组治疗后Rho激酶活性、硫酸吲哚酚(IS)水平、和肽素水平、脑钠肽(BNP)水平低于治疗前,观察组低于对照组,差异均有统计学意义(P<0.05);观察组慢性病二级管理不良事件发生率低于对照组,差异有统计学意义(P<0.05)。结论:辛伐他汀可能具有器官保护作用,可能与其可以改善血管功能有关。
作者 景秉莉
出处 《中国社区医师》 2019年第16期14-14,16,共2页 Chinese Community Doctors
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