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乳腺硬化性腺病基础上的低级别腺鳞癌一例 被引量:4

Low grade adenosquamous carcinoma arising from sclerosing adenosis of the breast: report of a case
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摘要 患者女,53岁,因发现"右乳肿块1个月余"就诊。肿物直径约1.3 cm,灰白色,质韧。镜下病变界尚清,2/3的区域为硬化性腺病,另1/3的区域硬化性间质中杂乱分布着小腺管以及鳞状分化细胞巢,鳞化细胞巢多呈实性条索状,部分形成大小不等的角化囊肿;病变细胞形态温和,核分裂象罕见,并见淋巴细胞聚集灶,局灶浸润周围组织。免疫组织化学显示该区域内大部分细胞巢周围缺乏p63、calponin及CD10染色,部分鳞状分化巢CK5/6和p63阳性,诊断为乳腺硬化性腺病基础上的低级别腺鳞癌。
作者 付丽梅 孙向洁 吕泓 水若鸿 徐晓丽 杨文涛 Fu Limei;Sun Xiangjie;Lyu Hong;Shui Ruohong;Xu Xiaoli;Yang Wentao(Department of Pathology, Fudan University Shanghai Cancer Center,Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Pathology, Binzhou People′s Hospital, Shandong Province, Binzhou 256600, China)
出处 《中华病理学杂志》 CAS CSCD 北大核心 2019年第5期415-417,共3页 Chinese Journal of Pathology
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