摘要
研究了以有机硅烷为还原剂选择性还原羰基的反应,在2.5mol% C6H5BF3K,2.2 epuiv.(EtO)3SiH作用下,甲醇为溶剂,室温下将羰基还原为醇.以中等至较高产率得到目标产物.该方法在羰基还原上表现出良好的选择性,为羰基还原提供了一种新的方法.
The selective reduction of carbonyl group with organosilane as reducing agent was studied with methanol as a solvent under the action of 2.5 mol% C6H5BF3K and 2.2 epuiv.(EtO)3SiH. The target products were obtained in medium to high yield. This method shows good selectivity and provides a new method for carbonyl reduction.
作者
刘建辉
王星旸
Liu Jianhui;Wang Xingyang(State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024;School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin Campus, Panjin 124221)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2019年第5期1411-1416,共6页
Chinese Journal of Organic Chemistry
基金
精细化工国家重点实验室(盘锦)(No.JH2014009)
重点大学基础研究基金资助项目~~
关键词
羰基还原
有机硅烷
苯基三氟硼酸钾
carbonyl reduction
organosilane
potassium phenyl trifluoroborate
