球囊扩张术治疗肌纤维发育不良型肾动脉狭窄的临床疗效

Clinical efficacy of balloon dilatation in treatment of renal artery stenosis resulting from fibromuscular dysplasia

目的评价肾动脉球囊扩张术治疗肾动脉肌纤维性发育不良(FMD)的疗效及安全性。方法选择诊断为FMD型肾动脉狭窄患者20例(均合并有不同程度高血压)行肾动脉球囊扩张术治疗,术后随访观察患者血压变化情况、药物治疗种类、术后再狭窄及其他并发症发生等情况。结果本研究手术技术成功率为100%(20/20),再狭窄率为15%(3/20)。术后随访平均(27.15±18.97)个月,治疗后收缩压、舒张压及服用降压药种类均低于治疗前,差异具有统计学意义(P<0.05)。无肾动脉破裂、夹层、分支堵塞及血栓形成等并发症及术后不良事件。结论球囊扩张术治疗FMD型肾动脉狭窄安全有效且预后较好,并发症较少。

Objective To evaluate the efficacy and safety of balloon dilatation in the treatment of renal artery stenosis fibromuscular dysplasia(FMD). Methods A total of 20 patients confirmed as FMD complicated with different degrees of hypertension were enrolled and treated with renal artery balloon dilatation. The blood pressure changes, drug treatment types, restenosis and other complications were observed during postoperative follow-up. Results The success rate of surgical technique in this study was 100%(20/20) and the restenosis rate was 15%(3/20). The average follow-up length was(27.15±18.97) months. The systolic blood pressure, diastolic blood pressure and antihypertensive drugs using were lower than those before treatment, and the differences were statistically significant(P<0.05).Conclusion Balloon dilatation is safe, effective, and has a good prognosis for FMD renal artery stenosis with fewer complications.