妇科恶性肿瘤化疗患者卵巢功能保护

Prevention of chemotherapy-induced ovarian damage in patients with gynecological malignant tumors

得益于肿瘤普查及诊断方法的进展,更多的妇科恶性肿瘤可在早期被发现。对于年轻患者,如何保留其卵巢功能及减轻后续的化疗对卵巢功能的损害,从而改善患者生存质量,提高生育能力显得尤为重要。文章针对妇科恶性肿瘤治疗过程中卵巢功能的保护,特别是化疗对卵巢的影响及其保护措施进行阐述。

Improvement in diagnosis has made it possible to have the early detection of gynecologic malignancies.Among premenopausal women,the loss of future fertility or ovarian function is considered among the most dreadful long-term side effects of treatments.Therefore,the preservation of fertility and ovarian function during chemotherapy treatment is of great important.This article will summarize the effect of chemotherapy on ovarian function and protective measures for chemotherapy-induced ovarian damage.