鸟类基因组核苷酸频数的进化模型

An Evolutionary Model of Nucleotide Frequency of Birds Genome

鸟类是四足类动物中最丰富的一类脊椎动物,本研究以12种鸟类的全基因组核苷酸序列数据为研究对象,建立核苷酸频数进化方程,研究了鸟类基因组核苷酸频数的进化机制和规律。通过拟合基因组数据确定了方程中的进化惯性参数、耗散参数和环境参数,估算出进化速率,得到了基因组长度随时间的演化曲线,解出了基因组在短时间内快速增加,信息快速积累,然后进入进化停滞阶段,核苷酸频数不再明显变化。本研究的方法为定量研究鸟类和一般物种的进化提供了新的思路。

Birds are the most abundant group of vertebrates among the tetrapods. In this study, the nucleotide sequence data of the whole genome of 12 species of birds were taken as the research object, and the evolution equation of nucleotide frequency was established to study the evolution mechanism and rule of nucleotide frequency in the bird genome. The evolutionary inertia parameters, dissipation parameters and environmental parameters in the equation were determined by fitting the genome data. This study estimated the evolution rate and obtained the evolution curve of genome length over time. The results showed that the genome increased rapidly in a short time, the information accumulated rapidly as well, and then entered the stage of evolutionary stagnation,and the frequency of nucleotides no longer changed significantly. The method of this study provides a new way to quantitatively study the evolution of birds and general species.