化学机械去腐技术治疗龋病的Meta分析

Meta-analysis of chemical-mechanical oral decontamination techniques for dental caries

目的评价化学机械去腐技术治疗龋病的应用价值与效果。方法首先使用计算机对数字化期刊全文数据库、中国期刊全文数据库以及中国生物医学文献数据库等进行文献检索;然后采用手检法,对计算机所检索出文章所附的参考文献和会议论文汇编进行补充。本研究主要分析比较了化学机械去龋技术与传统机械去腐技术治疗龋病的效果,通过与传统机械去龋效果的比较印证新型化学机械去龋的应用前景。并对纳入研究的文献采用Cochrane系统评价方法进行评价,并用RevMan5.2进行Meta分析。化学机械去腐评价指标包括了术后并发症、去腐时间、去腐效果以及疼痛程度、1年成功率等。结果化学机械去腐与常规去腐相比,去腐效果[OR=1.12,95%CI:(0.71,1.78),P=0.063]、继发龋发生率[OR=0.64,95%CI:(0.36,1.15),P=0.130]比较差异无统计学意义;去腐时间[OR=2.77,95%CI:(2.35,3.18),P<0.05]、疼痛发生率[OR=0.130,95%CI:(0.10,0.16),P<0.05]、牙髓并发症的发生率[OR=0.24,95%CI:(0.08,0.72),P<0.05]、牙科焦虑症的发生率[OR=0.19,95%CI:(0.12,0.28),P<0.05]、1年成功率[OR=1.81,95%CI:(1.08,3.04),P<0.05]比较差异有统计学意义。结论化学机械去腐与常规机械去腐相比,治疗效果差异无统计学意义,治疗时间有所增加,但可以降低疼痛、牙髓并发症以及牙科焦虑症的发生率,并且增加1年成功率。

Objective To evaluate the application value and effect of chemical-mechanical detoxification in the treatment of rickets. Methods Firstly, the computer was used to search the digital journal full-text database, the Chinese journal full-text database and the Chinese biomedical literature database. Then the manual examination method was used to supplement the reference documents and conference papers attached to the computer. In this paper, the effect of chemical-mechanical decontamination technology in the treatment of rickets is mainly analyzed. The paper confirmed the application prospect of new chemical-machinery decontamination. The literature included in the study was evaluated using the Cochrane systematic review method and Meta-analysis was performed using RevMan 5.2. The evaluation indexes of chemical-mechanical decontamination include postoperative complications, time of decontamination, decontamination effect and degree of pain, and 1-year success rate. Results When compared chemical-mechanical decontamination and the conventional decontamination, the decontamination effect [OR=1.12, 95% CI:(0.71, 1.78), P=0.063], incidence of secondary sputum [OR=0.64, 95% CI:(0.36, 1.15), P=0.13], P>0.05, the difference was no statistical significance. The decontamination time [OR=2.77, 95% CI:(2.35, 3.18), P<0.05], incidence of pain [OR=0.13, 95% CI:(0.10, 0.16), P<0.05], incidence of pulp complications [OR=0.24 95% CI:(0.08, 0.72), P<0.05], the incidence of dental anxiety [OR=0.19, 95% CI:(0.12, 0.28), P<0.05], 1-year success rate [OR=1.81, 95% CI:(1.08, 3.04), P<0.05], the difference were all statistically significant. Conclusion As compared with conventional mechanical decontamination, chemical-mechanical decontamination has no significant difference in the treatment effect. Through the treatment time is increased, but it can reduce the incidence of pain, pulp complications and dental anxiety, and increase the success rate of one year.