药学服务对提高慢性乙型肝炎患者用药依从性的效果影响

Influence of Pharmaceutical Care on Improving Medication Compliance in Patients with Chronic Hepatitis B

目的:探究药学服务前后对提高慢性乙型肝炎(CHB)患者抗乙肝病毒药物用药依从性的影响。方法:定期给CHB患者用药宣教和指导,并参与临床医生完善诊疗方案,针对患者给予个体化药学服务;比较药学服务前后CHB的用药认知度、病毒载量的控制、用药依从性的差异,以及患者对药学服务的需求。结果:药学服务后12月,患者对抗乙肝病毒药物的认知度、药学服务的需求和用药依从性明显提高,病毒载量也得到了有效控制。结论:药学服务的参与提高了CHB患者抗乙肝病毒药物用药的认知度和治疗的依从性,对降低了病毒载量(HBV-DNA)具有积极的临床意义。

Objective:To explore the effect of pharmaceutical care before and after on the improvement of antiHBV drug compliance in chronic hepatitis B(CHB)patients.Methods:Regular medication instruction and guidance for CHB patients,and participating in clinical doctors to improve the diagnosis and treatment program,and providing individual pharmaceutical care for patients;comparing the difference before and after the pharmaceutical care of the patients medication awareness,the viral load control,the medication compliance of CHB,and the demands for pharmaceutical care.Results:After 12 months of pharmaceutical care,the patients’awareness of anti-hepatitis B drugs,the demands for pharmaceutical care and the compliance with medication were significantly improved,and the viral load was effectively controlled.Conclusion:The participation of pharmaceutical care improves the awareness and compliance of CHB patients with anti-HBV drugs,and has a positive clinical significance in reducing the viral load(HBV-DNA).