血清中WBC、CRP和PCT检测对细菌性肺炎的临床价值

The clinical value of serum WBC,CRP and PCT in bacterial pneumonia

目的探讨血清白细胞计数(WBC)、C-反应蛋白(CRP)和降钙素原(PCT)对细菌性肺炎的临床价值。方法本院2015年5月-2017年9月收治肺炎患者160例,其中包括细菌性肺炎100例,非细菌性肺炎60例,选择同时期健康体检者60例,作为对照组,分别测定WBC、CRP、PCT的水平,同时比较细菌性肺炎患者预后不同指标的差异。结果与对照组比较,细菌性肺炎组和非细菌性肺炎组WBC、CRP和PCT这三项水平均升高(Ps<0.05),且细菌性肺炎组这三项指标水平均显著高于非细菌性肺炎组(Ps<0.05)。在细菌性肺炎组中,死亡者的这三项指标均明显高于存活者(Ps<0.05)。在单项检测中,PCT敏感性和特异性最高,WBC最低(Ps<0.05);三项联合检测敏感性和特异性高于单项检测(Ps<0.05)。结论血清中WBC、CRP和PCT这三项指标对细菌性肺炎的诊断和预后有一定评估价值。

Objective To evaluate the clinical value of serum white blood cell count(WBC),C-reactive protein(CRP),procalcitonin(PCT)in bacterial pneumonia. Methods 160 patients with pneumonia in our hospital from May 2015 to September 2017 were selected and divided into bacterial pneumonia group(100 cases)and non-bacterial pneumonia(60 cases).60 healthy examinees in the same period were selected as the control group.The levels and positive rates of WBC,CRP and PCT were detected,and the differences in different prognostic indicators among patients with bacterial pneumonia were compared. Results Compared with the control group,the levels of WBC,CRP and PCT in the bacterial pneumonia group and the non-bacterial pneumonia group increased(Ps<0.05). The three indexes in the bacterial pneumonia group were significantly higher than in non-bacterial pneumonia group(Ps<0.05).In the bacterial pneumonia group,these three indexes of deaths were significantly higher than those of survivors(Ps<0.05).In the single detection,the sensitivity and specificity of PCT were the highest,while those of WBC was the lowest(Ps<0.05). The sensitivity and specificity of combined detection were significantly higher than those of single detection(Ps<0.05). Conclusion WBC,CRP and PCT in serum are valuable for the diagnosis and prognosis of bacterial pneumonia.