IOLMaster700与IOLMaster500眼轴测量的一致性评价

Agreement of axial length measurements between IOLMaster 700 and IOLMaster 500

目的评价基于扫频OCT技术的IOLMaster700与IOLMaster 500对术后眼眼轴测量的一致性。设计诊断试验。研究对象单一眼科手术术后患者88例(109眼)。方法根据眼科手术类型将患者分为准分子激光角膜屈光手术后、有晶状体眼人工晶状体植入术后、白内障摘除术后、白内障摘除人工晶状体植入术后、玻璃体切除术后、玻璃体切除硅油填充术后6组。采用IOLMaster700和IOLMaster500,由一名有经验的技术人员在同一时间测量各组患者的眼轴长度(AL)。采用配对样本t检验分析两种不同仪器测量结果的差异性,采用组内相关系数(ICC)和Bland-Altman分析进行一致性评价。主要指标 AL,ICC和Bland-Altman分析结果。结果准分子激光角膜屈光手术后组和白内障摘除人工晶状体植入术后组中两种仪器所测得的AL差异具有统计学意义(P<0.001)。各组ICC为0.999~1.000,95%CI为0.998~1.000。Bland-Altman分析显示各组AL测量值差值95%一致限(LoA)最大绝对值为0.014~0.089。结论 IOLMaster 700与IOLMaster 500对眼科术后患者眼轴测量具有较好的一致性。

Objective To investigate the agreement of axial length (AL) measurements between IOLMaster 700 and IOLMaster 500 in postoperative patients. Design Diagnosis test. Participants A total of 109 eyes from 88 postoperative patients in Beijing Tongren Hospital. Methods Postoperative status included LASIK, aphakic, phakiciol, pseudophakic, postvitrectomy, and siliconoil. Measurements of AL examined with IOLMaster 700 and IOLMaster 500 by an experienced technician in the same time. The paired t test, the intraclass correlation coefficient (ICC) and Bland-Altman analysis were used to evaluate the agreements of the AL measurements between the two devices. Main Outcome Measures The AL measurements, the ICC, and Bland–Altman analysis. Results There were significant differences between the results of the two devices in post-LASIK and pseudophakic (P<0.001). Good agreements were indicated by the ICC(0.999 to1.000)and 95%CI(0.998~1.000). Bland-Altman analysis showed that the maximum absolute values of 95% limits of agreement (LoA) were small (0.014~0.089). Conclusion In postoperative patients, the agreement of AL measurements between IOLMaster 700 and IOLMaster 500 was excellent.