磁共振波谱分析在前列腺特异性抗原异常前列腺疾病患者中的临床诊断意义

Clinical significance of magnetic resonance spectroscopy in patients with prostate specific antigenabnormal prostate

目的研究分析磁共振波谱分析对前列腺特异性抗原(PSA)异常前列腺疾病患者的临床诊断意义。方法随机选取2017年1月至2018年12月潍坊市人民医院收治的经PSA检查均提示异常,具备穿刺指征行前列腺穿刺的患者作为研究对象,其中经穿刺术后明确诊断前列腺癌44例,前列腺增生93例。所有患者术前均行磁共振平扫+强化+波谱分析检查,通过对比分析得出磁共振平扫+强化+波谱分析联合检查的诊断价值。结果磁共振平扫+强化检查灵敏度77.3%(34/44)、特异度86.0%(80/93)、准确度83.2%(114/137);波谱分析检查灵敏度52.3%(23/44)、特异度77.4%(72/93)、准确度69.3%(95/137);二者联合应用的灵敏度90.9%(40/44)、特异度91.4%(85/93)、准确度91.2%(125/137)。结论磁共振波谱分析的应用,可增加磁共振平扫、强化检查诊断前列腺癌的灵敏度、特异度、准确度。

Objective To evaluate the diagnostic value of magnetic resonance spectroscopy analysis in patients with prostate specific antigen (PSA) abnormal prostate disease. Methods The patients who had abnormal PSA from January 2017 to December 2018 in Weifang People′s Hospital were selected. Patients with prostate puncture indications were as research target. A total of 137 patients including 44 patients with prostate cancer and 93 patients with benign prostatic hyperplasia were diagnosed by puncture. All patients underwent magnetic resonance scan and enhancement and spectroscopy before surgery. The comparative value of magnetic resonance scan+enhancement, magnetic resonance spectroscopy and joint examination was obtained. Results Sensitivity of magnetic resonance imaging and enhancement was 77.3%(34/44), specificity was 86.0%(80/93), and accuracy was 83.2%(114/137). Sensitivity of magnetic resonance spectroscopy was 52.3%(23/44), specificity was 77.4%(72/93), and accuracy was 69.3%(95/137). The sensitivity of the combined application was 90.9%(40/44), specificity was 91.4%(85/93), and accuracy was 91.2%(125/137). Conclusions The application of magnetic resonance spectroscopy can increase the sensitivity, specificity and accuracy of magnetic resonance plain scan and intensive examination for diagnosis of prostate cancer.