血管生成素样蛋白2在2型糖尿病中的研究进展被引量：3

Research progress of angiopoietin-like protein 2 in type 2 diabetes mellitus

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摘要血管生成素样蛋白2(ANGPTL2)是一种结构类似于血管生成素的分泌型循环糖蛋白,属于血管生成素样蛋白家族,其表达与肥胖症、胰岛素抵抗、2型糖尿病及其并发症等疾病密切相关。因此,ANGPTL2是糖尿病领域新的研究热点。本文就ANGPTL2的生物学特性、其在2型糖尿病及并发症中的研究进展进行综述。 Angiopoietin-like protein 2(ANGPTL2),a secreted circulating glycoprotein,belongs to a family of proteins structurally similar to the angiopoietins.It has been reported that the expression of ANGPTL2 is associated closely with obesity,insulin resistance,type 2 diabetes mellitus and its complications.So,the molecule becomes a research hotspot in the field of diabetes mellitus.This paper reviews the biological characteristics of ANGPTL2 and its research progress in type 2 diabetes mellitus and its complications.

作者雷云震简伟明侯莉明李俊王晓明 LEI Yun-Zhen;JIAN Wei-Ming;HOU Li-Ming;LI Jun;WANG Xiao-Ming(Department of Geriatrics,Xijing Hospital,Air Force Medical University,Xi’an 710032,China)

机构地区空军军医大学西京医院老年病科

出处《中华老年多器官疾病杂志》 2019年第6期460-463,共4页 Chinese Journal of Multiple Organ Diseases in the Elderly

基金国家自然科学基金(81870184)~~

关键词血管生成素样蛋白2 胰岛素抵抗糖尿病 2型 angiopoietin-like protein 2 insulin resistance diabetes mellitus,type 2

分类号 R587.1 [医药卫生—内分泌]

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