富勒烯羰基内酰胺化合物的亲电芳香取代反应研究

The Electrophilic Aromatic Substitution Reaction of N-MEM-ketolactam Fullerene Derivative

氮杂富勒烯是目前被重点关注的一类杂富勒烯,在化学合成方法中均需要经过开孔衍生物,然而对于氮杂富勒烯的前体开孔化合物—羰基内酰胺衍生物,人们的研究报道较少。本研究对其与富电子芳烃的亲电芳香取代反应进行了系统的研究。研究发现,反应除了生成单取代芳基氮杂[60]富勒烯,还有两个副产物。本论文对两个副产物进行了详细的表征和结构鉴定,这对后续开展氮杂富勒烯的深入研究提供了有利条件。

Azafullerene is one of the heterofullerenes which has been paid much attention.Open-cage fullerene derivatives are key intermediates to form aza[60]fullerene.However,the research of N-MEM-ketolactam derivative which is the precursor compound of azafullerene,is still quite rare.In this study,the electrophilic aromatic substitution reaction of N-MEM-ketolactam derivative with electron-rich aromatic hydrocarbons was extensively studied.The results indicate that the reaction afforded the monosubstituted aza[60]fullerene along with other two new by-products.Both of the by-products have been isolated and characterized.The research is very helpful in exploring their applications in materials science.