摘要
目前抗肿瘤药物的需求依然非常急迫,有研究表明,含氟配合物具有良好的生物活性。本文选择了2-氨基-4-三氟甲基苯甲酸与2,4-二羟基苯甲醛进行缩合,并选择邻菲罗啉作为第二配体,合成了六种新型的含氟席夫碱配合物,为未来研究新型抗肿瘤药物提供可行性方向。
The demand for anti-tumor drugs is still very urgent.Some studies have shown that fluorine-containing complexes have good biological activity.In this paper,2-amino-4-trifluoromethylbenzoic acid was condensed with 2,4-dihydroxybenzaldehyde,and phenanthroline was selected as the second ligand.Six new fluorine-containing Schiff bases complexes were synthesized.Cooperate to provide a feasible direction for the future research of new anti-tumor drugs.
作者
牛传凤
Niu Chuanfeng(Ocean University of China,Qingdao 266100,China)
出处
《山东化工》
CAS
2019年第9期69-70,74,共3页
Shandong Chemical Industry
