慢阻肺合并呼吸衰竭患者的无创呼吸机治疗效果

Experience of non-invasive ventilator therapy in chronic obstructive pulmonary disease complicated with respiratory failure

目的:探讨无创呼吸机治疗慢阻肺合并呼吸衰竭患者的临床效果。方法:将220例慢阻肺合并呼吸衰竭患者随机分为两组各110例,对照组仅限于常规内科综合治疗,观察组在其基础上进行无创正压通气。比较治疗前后的呼吸频率(respiratory rate,RR)、动脉血气指标及气管插管率、住院时间。结果:两组治疗后RR、pH、PaO2、PaCO2均改善(P<0.05),观察组比对照组改善更明显(P<0.05);观察组插管率与住院时间均少于对照组(P<0.05)。结论:无创正压通气是治疗慢阻肺合并呼吸衰竭的有效手段,可显著改善患者的呼吸和血气指标,减少气管插管痛苦。

Objective:To explore the clinical effect of non- invasive ventilator therapy in chronic obstructive pulmonary disease (COPD) complicated with respiratory failure. Methods:220 COPD patients with respiratory failure were randomly divided into two groups, with110 cases in each group. The control group was only treated with conventional internal medicine, while the observation group was treated with non-invasive positive pressure ventilation. Respiratory rate (RR), arterial blood gas index, tracheal intubation rate and hospitalization time were compared before and after treatment. Results:RR, pH, PaO2and PaCO2 in the two groups were significantly improved after treatment ( P <0.05), and the improvement in the observation group was more obvious than that in the control group ( P <0.05). Tracheal intubation rate and hospitalization time in observation group were significantly less than those in control group ( P <0.05). Conclusion:Non-invasive positive pressure ventilation is an effective method in COPD complicated with respiratory failure. It can significantly improve the respiratory and blood gas indexes and reduce the pain of tracheal intubation.